Radiesse®
Collagen-Stimulating Biostimulant

Skin & Structural Concerns

  • Loss of skin firmness and elasticity
  • Facial volume depletion and contour changes
  • Jawline, chin, and lower-face definition
  • Neck and décolleté laxity
  • Hand rejuvenation
  • Early to moderate skin aging

Skin Type

Most skin tones

Duration

30–45 minutes

Downtime

Minimal

Discomfort

Mild; numbing used

Longevity

12–18 months

Technology

Calcium Hydroxylapatite (CaHA) biostimulant

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Before & After

Radiesse® delivers immediate support and progressive collagen stimulation, improving skin firmness, contours, and overall quality over time.

BEFORE

AFTER

BEFORE

AFTER

BEFORE

AFTER

Benefits of Radiesse®

  • Stimulates natural collagen production for long-term skin improvement.
  • Provides immediate structural support with gradual biostimulation.
  • Improves firmness and elasticity without overfilling.
  • Defines facial contours such as jawline and chin.
  • Rejuvenates hands, neck, and décolleté.
  • Long-lasting results up to 18 months.
  • Physician-controlled placement for natural outcomes.

Treatment & Technology

What is Radiesse®?

Radiesse® is an FDA-approved biostimulant injectable made of calcium hydroxylapatite (CaHA) microspheres suspended in a gel carrier. It provides immediate support while stimulating the body’s natural collagen production over time.

How it works
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After injection, Radiesse® offers instant support. Over the following weeks, CaHA microspheres stimulate fibroblasts to produce new collagen, improving skin thickness, elasticity, and firmness.

As the gel carrier is naturally absorbed, newly formed collagen replaces it, resulting in gradual, natural-looking rejuvenation without overfilling.

Radiesse® Dermal Filler can treat the following areas

Corners of the Mouth

Lines called oral commissures give the mouth a downturned appearance, which can make you look tired, angry, or sad.

Marionette Lines

Lines under your mouth can make you look like you’re scowling, even when you’re not.

Pre-jowl Folds

The areas on either side of the chin can look hollow as volume loss causes the skin to sag along your jawline and create folds.

Chin Wrinkles

The lines across your chin can distract from your smile and make you look older.

Smile Lines

Deep smile lines, called nasolabial folds can give your face a tired and aged expression.

Radiesse (+) can improve jawline contour:

  • For adults over the age of 21
  • Effective improvement in moderate to severe loss of jawline contour

Radiesse can enhance the appearance of hands by:

  • Restoring volume loss, which contributes to the signs of aging
  • Minimizing the visibility of veins and tendons

How Radiesse® Stands Apart

Not all injectable treatments work the same way. Here’s how Radiesse® compares to other commonly used dermal fillers and biostimulants.

Juvederm®

Type: Gel-based filler
Purpose: Instant volume & contour
Results: Immediate, temporary
Longevity: ~6–12 months
Best for: Lips, fine lines, soft volume
Key limitation: No collagen stimulation

Radiesse®

Type: Calcium Hydroxylapatite (CaHA) biostimulant
Primary role: Structural support + collagen stimulation
Mechanism: Provides immediate support while stimulating natural collagen over time
Longevity: ~12–18 months
Results: Immediate definition + progressive skin tightening
Best for: Jawline, chin, neck, lower face, hands, skin firmness
Downtime: Minimal

Sculptra®

Type: PLLA biostimulant
Purpose: Gradual collagen rebuilding
Results: Slow, progressive over months
Longevity: Up to 2+ years
Best for: Large-volume correction
Key limitation: No immediate results

Recovery and Aftercare

Immediately: return to normal activities.

Expected: mild swelling, redness, or tenderness.

Bruising: possible; resolves within days.

Aftercare: avoid pressure or massage for 24–48 hours.

First 48 Hours
Avoid intense exercise • No massage • SPF daily

Your provider may tailor aftercare based on treatment area.

Frequently Asked Questions

Radiesse® is used to restore facial structure, improve skin firmness, stimulate collagen production, and rejuvenate areas such as the jawline, chin, neck, décolleté, and hands.

Radiesse® functions as both. It provides immediate structural support while also acting as a biostimulant that stimulates your body’s natural collagen production over time.

Results typically last 12–18 months, depending on the treatment area, technique used, and individual factors such as metabolism and skin quality.

Yes. Radiesse® is FDA-approved and has a long history of safe use when administered by trained medical professionals. It has been used worldwide for both facial and non-surgical rejuvenation.

Yes. Radiesse® results develop gradually through collagen stimulation, which helps avoid an overfilled or artificial appearance. Skin quality and firmness improve progressively over time.

Downtime is minimal. Mild swelling, tenderness, or bruising may occur and typically resolves within a few days. Most patients return to normal activities shortly after treatment.

Radiesse® is ideal for patients experiencing volume loss, skin laxity, or early structural aging who want long-lasting, natural-looking results without surgery.

Yes. Radiesse® is commonly combined with neuromodulators (such as Botox®), laser and energy-based treatments, skin boosters, and other aesthetic procedures as part of a customized treatment plan.

Traditional dermal fillers, such as hyaluronic acid fillers, primarily work by adding volume to specific areas of the face. Radiesse® differs in that it is a biostimulant designed to strengthen skin structure and stimulate collagen production.

While Radiesse® provides some immediate support, its main benefit is long-term improvement in skin firmness, elasticity, and overall quality as new collagen forms.

Juvederm® and other hyaluronic acid fillers are gel-based products that add volume and attract water to smooth lines and enhance contours.

Radiesse® is made of calcium hydroxylapatite (CaHA) microspheres that stimulate collagen production. It focuses more on structural support and skin tightening rather than soft, gel-based volume alone.

In many cases, yes. Radiesse® results often last longer — typically 12–18 months — compared to many hyaluronic acid fillers, which usually last 6–12 months.

This extended longevity is due to Radiesse®’s collagen-stimulating effect, which continues even after the product itself is absorbed.

Both treatments can look natural when properly performed. Radiesse® often creates a more gradual, natural-looking improvement because results develop over time through collagen regeneration rather than instant volume alone.

Yes. Radiesse® and hyaluronic acid fillers are frequently combined in a comprehensive treatment plan.

Radiesse® may be used to improve skin firmness and structure, while hyaluronic acid fillers are used for precise volume or contouring in areas such as lips or fine lines.

The best treatment depends on your facial anatomy, skin quality, and aesthetic goals. Radiesse® is often recommended for patients seeking skin tightening, collagen stimulation, and longer-lasting support.

A consultation with a qualified medical provider is essential to determine the safest and most effective option for you.